Galangal: The Best Cancer-Fighting Herb Around?

This article was originally published by our friend Dr. Axe

What looks like ginger, acts a little bit like turmeric, but actually has been shown to fight cancer like a champ and can even keep your brain healthy? You (probably haven’t) guessed it: galangal.

This root, part of the ginger family, grows in various parts of Asia and is a staple herb in Thai cooking. The best part about galangal, though, is the way it fights to keep your body healthy. It’s been found to have significant positive effects on eight different types of cancer as well a reduce chronic and specific forms of inflammation, often better than medication.

So, let’s take a journey to explore this herb and exactly how it can benefit your health.


What Is Galangal?

I promise, I’m not trying to fool you — this is not ginger. In fact, galangal is called for in many of the same Asian recipes as ginger because they have significantly unique flavors.

This root spice originated in China and Thailand, making its way into common Ayurvedic medicine. Many people describe its flavor as simultaneously earthy and citrus-like, with a spicy kick. However, galangal isn’t spicy due to capsaicin, like most spicy foods. Instead of leaving you with a lasting burning sensation, it hits you and goes away immediately.

If you’re into Thai food and have tried tom ka gai, a popular Thai soup dish, you may recognize the flavor of galangal root as that peculiar flavor you simply couldn’t place. Well, now that we’ve figured that out, what’s it good for?

The answer to that question may intrigue you, because, in short, it’s good for a lot.

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7 Benefits of Galangal

1. Potentially Revolutionary Cancer-Fighting Agent

The most striking health benefit of galangal, according to a massive (and growing) body of scientific research, is its ability to fight and potentially prevent a broad number of cancers and tumors. (1) I’ll review the types of cancer affected by galangal, one by one.

Gastric Cancer

A 2014 study in Iran found that a liquid extract of galangal significantly destroyed the number of gastric cancer cells in a lab test after 48 hours, calling it a “prominent” result. (2)

Leukemia

Acute monocytic leukemia cells, a fast-moving leukemia that begins in the bone marrow, were exposed to a liquid extract of galangal in an effort to find a natural cancer treatment that wouldn’t damage adjoining cells, like dangerous chemotherapy. The researchers in Jamaica conducting the study suggested that this could be a potential cure for this form of leukemia, and that’s not a word scientists use lightly. However, this study was simply the beginning, as much more research must be done to examine the effects of this extract on healthy cells before testing it in living subjects. (3)

Melanoma

Researchers at National Chiayi University in Taiwan studied the impact of three compounds from galangal root on human melanoma (skin cancer) cells. All three compounds had an “antiproliferative” effect, meaning they stopped the growth of new cells. (4)

Pancreatic Cancer

A study released in 2017 tested multiple compounds from galangal in the lab and their impact on pancreatic cancer cells, finding they stopped the growth of new cells and suppressed gene pathways responsible for expanding the cancer’s impact. (5)

Colon Cancer

The first time galangal was studied against human colon cancer cells (in 2013), scientists found it caused apoptosis (cell death) on two types of colon cancer cells. (6)

Breast Cancer

In 2014, an Iranian university found that an extract of galangal spawned apoptosis in the human breast cancer cell line, MCF-7, but did not harm healthy breast cells, MRC-5. (7) Diving more into the method by which galangal achieves this, a medical university study out of China found that it used the TRAIL pathway of cancer treatment to stimulate cell death in breast cancer cells. (8)

Liver (Hepatic) Cancer

One reason cancer is so devastating to the human body has to do with the way it spreads or “metastasizes” to other organs from where it originates. This is especially true with liver cancer. A Taiwan study in 2015 investigating the impact of galangal extracted compounds on HepG2 cells (a type of liver cancer) found that the natural compounds decreased the instance of metastasis by stopping the cells from attaching to other, healthy cells. (9)

In another study related to liver cancer, combination therapy was used with galangal and more common therapy agents, producing an apoptotic effect more significant than the individual therapies displayed. (10)

Cholangiocarcinoma (Bile Duct Cancer)

This particular form of cancer is not as common in the U.S., but it’s an aggressive cancer that infects the bile ducts connecting the liver to the small intestine. It impacts people more commonly in tropical and sub-tropical regions, especially Thailand. The kaempferol rhizome extract from galangal tested in a 2017 Thailand-based study gave the mice subjects longer life spans, less incidence of metastasis and did not produce any noticeable side effects on the subjects. (11)

2. Improves Sperm Count and Function

Certain parts of the galangal root may prove useful in promoting male fertility. In a rat model, researchers in Iran discovered that it increased sperm count and motility (or ability to move). (12)

One study in Denmark looked into the effect a galangal rhizome, paired with a pomegranate fruit extract, had on sperm in healthy human males. Researchers found that the the number of motile sperm increased by three times the amount of the placebo. (13)

3. Acts as an Anti-Inflammatory Agent

Inflammation is at the root of most diseases. This means that chronic inflammation is related to the development of a large number of diseases, including cancer, heart disease, Alzheimer’s disease and several others. Galangal root exhibits an anti-inflammatory effect on the body in a general manner and against specific conditions. (14)

There is a cytokine (cell-signaling protein) found in the human body known as tumor necrosis factor alpha, or TNF-alpha, which regulates immune response. This protein is the subject of a great deal of research because TNF-alpha, if overstimulated, can cause detrimental damage and contribute to fatal diseases with chronic inflammation. A phytonutrient found in galangal suppresses the activity of TNF-alpha and therefore may help reduce inflammation throughout the body. (15)

This herb may also help reduce the inflammation associated with arthritis. In a 2001 study, subjects taking a compound including galangal and ginger extract saw a significant reduction in knee pain and in the need for medications and overall status. (16)

Another condition that may be successfully treated with one of the phytonutrients in this herb (kaempferol) is mastitis. Mastitis is an inflammation of the nipple related to breastfeeding. When treated with kaempferol, the mice in one study found a great reduction in inflammation (related, at least in part, to the suppression of TNF-alpha) to the point that it may be a significant treatment in the future for this condition. (17)

One more particularly significant condition that may benefit from galangal treatment is acute lung injury leading to acute respiratory distress syndrome. This illness is somewhat common, especially among those who are already critically ill, and occurs when fluid leaks into the lungs and stops oxygen from being transferred to vital organs. Unfortunately, acute lung injury is often fatal. (18)

However, galangal’s anti-inflammatory activity seems to have a positive impact on acute lung injury and may be a significant treatment option in the future. (19)

4. Has Antibacterial and Antifungal Qualities

Galangal extract exerts an antimicrobial effect on several bacteria known for infecting foods, including staphylococcus, E. coli, listeria, salmonella and clostridium. (20) It can even fight amoxicillin-resistant E. coli and actually reverse the resistance some strains have to amoxicillin. (21)

By cooking shellfish with this herb, you may also have a better chance of inhibiting the impact of a bacteria known as vibrio. Vibriosis can affect those who eat undercooked shellfish, particularly oysters, but those effects may be much less likely after adding galangal to your recipe. (22)

Another common bacteria that is, in fact, carried by about 66 percent of the world’s population (according to the Centers for Disease Control and Prevention) is called H. pylori. However, this bacteria may also have met its match when exposed to galangal — in fact, this powerful herb may even help prevent the stomach ulcers commonly caused by the H. pylori bacteria in addition to eliminating the bacteria itself. (23)

5. High in Antioxidants

While we know eating blueberries help us increase our antioxidant intake, you may be interested to know the same is true with galangal — although the types of antioxidants found in it aren’t necessarily the same as those found in fruits you love. Interestingly, the antioxidants in this herb seem most effective in preserving meat products for longer periods of time than without it. (2425)

6. Supports Good Brain Health

Potentially due partly to its anti-inflammatory properties, a compound taken from this root known as ACA could possibly have a brain-protecting effect, decreasing some forms of age-related cognitive degeneration. (26)

Circling back to the TNF-alpha protein, we also find that by regulating TNF-alpha, galangal may even help fight depression. Chronic inflammation and the overreaction of TNF-alpha is a recently studied facet of the discussion surrounding depression. (27)

7. May Ease Stomach Pain and Digestive Issues

While it’s obvious that this root has incredible benefits according to modern science, its oldest and most commonly sought effect is that which it has on an upset stomach. In Ayurvedic medicine and other Asian cultures, it’s used to calm upset stomachs, resolve diarrhea, reduce vomiting and even stop hiccups. (28)


Galangal Nutrition Facts

While galangal and ginger are two different roots, they do come from the same family. “Galangal” refers to any one of four plant species in the Zingiberaceae family: Alpinia galanga (greater galangal), Alpinia officinarum (lesser galangal), Kaempferia galanga (kencur, black galangal or sand ginger) or Boesenbergia rotunda (Chinese ginger or fingerroot). Most scientific research focuses on either the greater or lesser plant species.

Like ginger, this root grows in rhizomes beneath the ground. While it’s not a staple in most Western cooking styles, it’s a common ingredient in Thai and traditional Chinese food.

The rhizomes contain a small amount of calories and other nutrients, although serving sizes vary per recipe and some may include only a minute amount of the spice.

One serving of galangal root (100 grams) contains about: (29)

  • 71 calories
  • 15 grams carbohydrate
  • 1 gram protein
  • 1 gram fat
  • 2 grams fiber
  • 5.4 grams vitamin C (9 percent DV)

Galangal vs. Ginger vs. Turmeric

Often compared to ginger and turmeric, galangal has many similarities to these other two incredibly common dietary condiments.

All three roots have at least some cancer-fighting properties (though galangal’s are the most extensive), reduce inflammation and offer some sort of digestive support. Both turmeric and ginger have been known to help combat diabetes and naturally manage pain, while there is no evidence as of yet that galangal does. Turmeric and galangal, because of their ability to suppress TNF-alpha, both help promote the health of the brain.

Turmeric alone of the three seems to benefit the health of the cardiovascular system. Ginger boasts a weight-loss aspect, and galangal promotes an increased sperm count.

Interestingly, while all three of these have gastrointestinal benefits, galangal may actually increase the amount of stomach acid in some individuals and is not recommended for people with GERD or peptic ulcer disease, whereas the other two can actually be used to treat those conditions.


How to Grow, Use and Cook Galangal

Generally, galangal requires a tropical environment in which to thrive, although it’s possible to grow in more temperate climates when protected from frost. To plant it, place rhizomes about eight inches apart in the early spring. When you’re ready to harvest, gently remove some of the outer rhizomes away from the center, rather than digging up the entire plant (but make sure to give your plant about 12 months to mature before beginning to harvest).

To maintain freshness, leave the skin on until you’re ready to use it. It will keep for several weeks in the refrigerator but can also be frozen or dried to extend shelf life. In cooking, you can use both the fresh herb and the dried rhizomes.

There are a few ways to utilize the root for consumption. One way is to actually chop up the roots and use them in a “decoction,” which simply means to create a “liquor” of sorts from the essence of the rhizome. You can also grind to a powder and create your own homemade supplements, create a tea or just chop or mince it for use in a variety of dishes.

In cooking, feel free to experiment with it. Research shows that many people actually show a taste preference for its pungent yet satisfying flavor, even over other spicy ingredients. (30)

Galangal Recipes

Ready to head over to your local Asian market? Good — you should be, because this stuff is awesome!

No recipe reference for galangal would be complete without a delicious Tom Ka Gai recipe, so let me know what you think of this one.

If you need to satisfy a Thai food craving but don’t have much time, I really enjoy this one-pot Creamy Thai Coconut Chicken Soup.

However, if you’re really up for a challenge, you can also try this Lobster Thai Curry with Galangal. Seafood, plus cancer-fighting nutrients, equals a great dinner.


Precautions

Like most herbs, you should avoid using galangal while pregnant, unless monitored closely by a physician.

Galangal is a relatively hypo-allergenic food, actually suggested in some texts to decrease the intensity of allergic reactions, so the chances are good that you won’t experience any allergy symptoms after consuming it. (32)

As I mentioned before, galangal (specifically Alpinia galanga, or “greater galangal”) may potentially increase the amount of stomach acid you produce. If you have GERD or peptic ulcer disease, it’s probably best to avoid this one unless recommended by your primary care physician. (33)


Final Thoughts

  • Galangal, part of the ginger family, is a savory and spicy herb originating from Thailand and China.
  • It’s one of the only flavors to add spice without the presence of capsaicin.
  • The most widely researched benefit of galangal is its ability to fight cancers.
  • Galangal also helps to reduce inflammation, increase sperm count and motility, fight bacterial and fungal infections, support brain health, and ease nausea and other stomach problems.
  • “Galangal” refers to any of four types of roots, the two most common being the lesser galangal and greater galangal.
  • Turmeric and ginger share some benefits and features with galangal, but all three have distinct flavors and some of their own unique pros.
  • It’s challenging but not impossible to grow galangal in less-than-tropic conditions, and you’ll need to wait a minimum of a year before harvesting any of your own to use.
  • Galangal is an ancient herb that’s been famous for centuries for its ability to treat various medical conditions.


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Dr. Josh Axe, DNM, DC, CNS, is a doctor of natural medicine, doctor of chiropractic and clinical nutritionist with a passion to help people get well using food as medicine and operates one of the world’s largest natural health websites: www.DrAxe.com.

He is the author of the groundbreaking health book Eat Dirt, which uncovers the hidden causes and cures of leaky gut syndrome. Dr. Axe is an expert in digestive health, functional medicine, natural remedies and dietary strategies for healing. He has been featured on many television shows, including the Dr. Oz Show, CBS and NBC, and has his own Eat Dirt program running on select PBS TV stations.

Dr. Axe founded one of the largest functional medicine clinics in the world, in Nashville, TN, and has been a physician for many professional athletes.

DrAxe.com is one of the most visited websites worldwide for healthy recipes, herbal remedies, nutrition and fitness advice, essential oils, and natural supplements.