Autophagy, Fasting & Exercise: Scientists Reveal Multiple Ways You Can Slow Down The Process of Aging

This article was originally published at Collective Evolution

Disease has been on the rise for multiple decades. It seems quite clear that things aren’t really getting any better, and with a growing population, the rate of chronic illness seems to be getting worse. On top of that, we have a medical ‘industry’ full of good-hearted people who want to help people, and are helping people, that’s plagued by fraud and deception. One that is not really interested in healing people, but rather, in profiting off of their sickness. There are countless instances of this. For example, a study that was published last week in the British Medical Journal by researchers at the Nordic Cochrane Center in Copenhagen showed that pharmaceutical companies were not disclosing all information regarding the results of their drug trials. You can read more about that and access the study here.

The medical profession is being bought by the pharmaceutical industry, not only in terms of the practice of medicine, but also in terms of teaching and research. The academic institutions of this country are allowing themselves to be the paid agents of the pharmaceutical industry. I think it’s disgraceful. — Arnold Seymour Relman (1923-2014), Harvard Professor of Medicine and Former Editor-in-Chief of the New England Medical Journal

The above study is one of many examples, with various medications for various diseases. This is extremely concerning, especially given the fact that various experts estimate more than 100,000 people die every year in the United States alone from prescription drug use. (source)

There doesn’t seem to be much attention paid to the environment we choose to surround ourselves with, the foods we eat, and detoxifying our bodies. The answer to everything from the world of medicine seems to come in the form of drugs, which is not always the best option depending on your situation.

Ask yourself: why are so many people getting sick all the time? Why is disease constantly on the rise? One explanation that many experts are putting forth is the environment. We live on a planet where simply breathing in the air from any major city is a health hazard. Our cosmetics, self-care products, and common everyday household products are littered with hormone disrupting chemicals, and the food most of us eat has been linked to multiple diseases. Roundup herbicide has been found in the urine of people across Europe, and the list goes on and on. It’s no secret that we are currently living in a toxic environment, and for those looking to stay in good health, detoxifying is something important we can to do instead of putting so much stress on our internal organs to do it on their own. We need to assist them and we can do it in several different ways.

Autophagy

The body does a great job of detoxifying itself on its own, and it’s quite amazing. Perhaps this is why some people can smoke, drink, and eat poorly for most of their life and still survive into old age, but that’s not true for the majority of people.

Autophagy means “self” eating, and it’s a process where your body cleans out various toxins and recycles damaged cell components.

The video above provides a more in-depth biochemical review of the autophagy processes involved in health and disease.

Dr. Colin Champ, a board-certified radiation oncologist and assistant professor at the University of Pittsburgh Medical Center explains it well:

Think of it as our body’s innate recycling program. Autophagy makes us more efficient machines to get rid of faulty parts, stop cancerous growths, and stop metabolic dysfunction like obesity and diabetes. (source)

One of the best ways to detoxify your system, and slow the aging process (thus greatly reducing the risk of various age-related diseases) is to assist your body in the process of autophagy.

Exercise 

Exercise is a great way to fight disease. Our bodies are built to move, which is something many people don’t do enough of. Exercising alone has been shown to kill cancer cells, because it’s an excellent way to boost the autophagy process.

Clinical trials were conducted to help detoxify people from the Gulf War, and in doing so, results showed that that using a combination of exercise, sauna (detox through sweating), and niacin supplementation, maximized the elimination of toxins through the skin. Not only that, exercise does cause an increase in blood flow and vasodilation.

Scientists have also engineered mice to have glowing green autophagosomes and found that the rate at which the mice were demolishing their own cells (in a healthy way) increased significantly after they ran for 30 minutes on a treadmill. The rate also continued to increase as they ran past the 30 minute mark.

All of this is discussed by Dr. Yu, in the interview below that was conducted with Dr. Joseph Marcela discussing those studies. You can check it out for more information.

Intermittent Fasting

A number of scientists have been studying fasting these days, and the results are quite remarkable to say the least. One thing it definitely does is boost autophagy. Fasting has a number of other benefits, including regenerating new stem cells, fighting cancer, and reducing the risk of diabetes and heart disease.

When you supply fuel to your mitochondria when they don’t need it, they leak electors that enhance reactive oxygen species as free radicals, and free radicals are extremely damaging. Supplying fuel to your mitochondria (via food) is the opposite of fasting.

Mitochondria is the power source to your cells, and these free radicals damage it.

Here is a video (TEDx) talk given by Mark Mattson, the current Chief of the Laboratory of Neuroscience at the National Institute on Aging. He is also a professor of Neuroscience at The Johns Hopkins University, and one of the foremost researchers in the area of cellular and molecular mechanisms underlying multiple neurodegenerative disorders, like Parkinson’s and Alzheimer’s disease. In it, he describes how fasting can reverse multiple age-related diseases.

Basically, when you take a look at caloric restriction studies, many of them show a prolonged lifespan as well as an increased ability to fight chronic disease.

Calorie restriction (CR) extends life span and retards age-related chronic diseases in a variety of species, including rats, mice, fish, flies, worms, and yeast. The mechanism or mechanisms through which this occurs are unclear.

The quote above is from a review of the literature that is more than 10 years old. The work presented here is now showing some of these mechanisms that were previously unclear.

A study published in the June 5 issue of Cell Stem Cell by researchers from the University of Southern California showed that cycles of prolonged fasting protect against immune system damage and, moreover, induce immune system regeneration. They concluded that fasting shifts stem cells from a dormant state to a state of self-renewal. It triggers stem cell based regeneration of an organ or system. (source)

Human clinical trials were conducted using patients who were receiving chemotherapy. For long periods of time, patients did not eat, which significantly lowered their white blood cell counts. In mice, fasting cycles “flipped a regenerative switch, changing the signalling pathways for hematopoietic stem cells, which are responsible for the generation of blood and immune systems.” (source)

This means that fasting kills off old and damaged immune cells, and when the body rebounds, it uses stem cells to create brand new, completely healthy cells.

We could not predict that prolonged fasting would have such a remarkable effect in promoting stem cell-based regeneration of the hematopoietic system. . . . When you starve, the system tries to save energy, and one of the things it can do to save energy is to recycle a lot of the immune cells that are not needed, especially those that may be damaged. What we started noticing in both our human work and animal work is that the white blood cell count goes down with prolonged fasting. Then when you re-feed, the blood cells come back.  – Valter Longo, corresponding author (source)

One well-known option is the “5:2 Diet.” On the 5:2 plan, you cut your food down to one-fourth of your normal daily calories on fasting days (about 600 calories for men and about 500 for women), along with plenty of water and tea. On the other five days of the week, you can eat normally. Another way to do it is to restrict your food intake between the hours of 11 am and 7 pm daily, while not eating during the hours outside of that time. This is also explained in the documentary below.

Watch What You Eat & Monitor Your Protein Intake

This is really a no-brainer: eating healthy organic fruits and vegetables is important. One factor to consider is your protein intake. Today we seem to be bombarded with the idea that a lot of protein is necessary, especially if you are working out quite a bit. Although this may be true, over doing it on protein is definitely not a good idea.

It’s important to watch your protein intake when talking about autophagy, because too much protein will shut down autophagy, which is why it might not be a bad idea to limit your protein intake to about 40-70 grams a day, depending on your body bass. The usual formula health experts use to calculate how much protein your body requires is one gram of protein for every kilogram of lean body ass, or one-half gram per pound of lean body mass.

One of the quickest ways to shut down autophagy is to eat large amounts of protein. What this will do is stimulate IGF-1 and mTOR, which are potent inhibitors of autophagy. This is expanded upon by the scientists in the documentary linked above if you’re interested in learning more.


11 pounds in 22 days?

baking soda

Is it REALLY possible to lose 11 lbs. of fat in 22 days?  Actually yes… BUT only when you’re a level 4 fat burner.  Unfortunately, most people are stuck as level 1 fat burners.  So, how do you become a level 4 fat burner to lose up to 11 lbs. in 22 days?  Simply eat these foods daily:

==> Lose up to 11 lbs. in 22 days by eating these foods daily (upgrades you to level 4 fat burning status)


Best stretch before bed (1 minute)

Did you know that one of the best times to stretch is right before bed? However…

What stretches should you do? Here’s a 1-minute stretch routine you can do before bed...

=> Best stretch before bed (takes 1-min)

Enjoy!

Lisa, Yoga Coach
eatlocalgrown / wisemindhealthybody


Stop Snoring in 3 Minutes - Starting Tonight

...easy, 3-minute exercise that completely cured his horrendous snoring! We can both finally sleep!

Today is a good day. Tonight will be even better. Why?

Because you're about to learn easy throat exercises that cure (not just treated) your stubborn snoring – in 3 minutes – starting TONIGHT!

...even if straps, sprays and even torturing CPAP masks have failed you in the past.

Most people heal their snoring in just a few minutes per day using these powerful throat exercises. And they're so easy, you can do them, regardless of your age or physical shape.

Use them anytimeanywhere... even while stuck in traffic or watching TV.

Plus the results are permanent!

To learn more and test-drive the easy snoring and sleep apnea exercises for yourself, click here...

To a good night's sleep,
Rick + Lisa
eatlocalgrown / wisemindhealthybody


The #1 "bodyfat-eating" hormone...

weight loss solved

Did you know that your bodyfat can become "calorie-resistant"?

True. And it's completely unaffected by even the strictest diets... and most intense exercises.

However, there's good news- Calorie-resistant bodyfat can be now removed...

It's a little-known, calorie-burning hormone we all have... just waiting for the right spark to come alive. It's not thyroid, leptin, ghrelin, insulin, adiponectin, HGH or any other "fat loss" hormone you may know. Read more to find out precisely how to unleash its calorie-burning power:

==> How to Activate Your #1 "Bodyfat-Eating" Hormone...

To your health!

PS - Studies show that it can also reduce your risk of diabetes by 53.7%, a heart attack by 83.3% and stroke by 51.4%. Here's more of the scientific proof...


#1 muscle that eliminates joint and back pain, anxiety and looking fat

I bet you can’t guess which muscle in your body is the #1 muscle that eliminates joint and back pain, anxiety and looking fat. This “hidden survival muscle” in your body will boost your energy levels, immune system, sexual function, strength and athletic performance when unlocked.

If this “hidden” most powerful primal muscle is healthy, we are healthy.

Is it…

a) Abs

b) Chest

c) Glutes

d) Hip Flexors

Take the quiz above and see if you got the correct answer!


How to Wipe Out Chronic Inflammation (Free Book)

inflammation

In April, 2009, researchers stunned the medical community when they reported chronic inflammation as the root cause of several major diseases.

See, every year 610,000 people in the U.S. die of heart disease. Cancer claims another 584,000...stroke 130,000...Alzheimer's disease nearly 85,000 — and the list goes on.

Truth is, we now know... chronic inflammation is responsible for 7 out of the top 10 leading causes of death in the United States! Hundreds of studies and scientific reviews prove it.

inflammation book

Fortunately, newer research shows you can prevent-even reverse-most major diseases by "turning off" inflammation. And in our new book, we show you how to do just that.

If you or a loved one is suffering from a debilitating condition-and you"re not sure what the culprit is-now's the time to find out...while you can still do something about it!

Get the Free Inflammation Book

--> Grab your FREE copy of this groundbreaking soft cover book today (while supplies still last.)


Free Paleo / Keto Cookbook

Over the past year, my friend Dave over at PaleoHacks has been working on a super secret cookbook project with our good friend Peter Servold ­­ a Le Cordon Bleu trained Chef and owner of Pete's Paleo...

And today, this new incredible Paleo Cookbook is finally available to be shipped right to your door for FREE!

paleohack chart

The cookbook is called Paleo Eats, and it's filled with over 80 chef ­created, insanely tasty Paleo recipes ­­ which means they are free from gluten, soy, dairy, and refined sugar.

Get your FREE copy of Paleo Eats Here. (Grab this today, because they only ordered a small batch of these cookbooks for this freebie promotion, and they will sell out FAST!)

>> Get The Free Cookbook

Enjoy!


Sponsored Health Resources

In the years that I've been working on this website project I've come across some amazing resources by some very special people. I'd like to share them with you here.

NOTE: I update these links often so please check back to see what's new!


1) Everyone knows green smoothies are healthy right? Have you heard of a “red” smoothie? If not, check out this story…

--> "Red" Smoothie Helps Alabama Girl Shed 80lbs!


2) Forget what you've read about 10-day lemonade cleanses, 7-day detoxes with green juices and Gwyneth's gruel. All you need to do, and this is perfect for Saturday or or anytime really, is a simple 1-day cleanse.

--> Get the 1 Day Cleanse (better than 7-day detoxes!)


3) This “hidden survival muscle” in your body will boost your energy levels, immune system, sexual function, strength and athletic performance when unlocked.

--> #1 muscle that eliminates joint and back pain, anxiety and looking fat


4) I thought it was virtually impossible for a website to be able to tell me anything even a little bit insightful after only submitting my name and date of birth... I was wrong!

--> Your Birth Date + Name - Free Report


5) Turmeric is amazing. The problem is - It's hard to absorb!

--> The best way to get maximum effects of Turmeric


6) Wonder why your stomach still sticks out even though you're hammering the core exercises every day? It's a common myth that bulging belly is due to weak abdominal muscles.

--> Why Some People LOOK Fat that Aren't


7) Even if you're the most active of athletes, you may still suffer from tight hip flexors due to the amount of time you spend each day planted to a chair.

-->  Unlock Your Hip Flexors


Enjoy! Let me know how these work out for you. And if you run across anything I've missed please let me know.

Rick D.
wisemindhealthybody.com