Cancer has become Americans’ No. 1 health concern. According to the American Cancer Society, more than 1,600 people die every day from cancer in the U.S. That’s over 600,000 people each year. When you include the entire world population that number climbs tenfold to over 7.6 million. Statistics suggest half of all men and 4 out of 10 women will develop cancer during their lifetimes.
Alzheimer’s disease is another major health threat that has dramatically increased in recent years. Between 1999 and 2014, the death rate from Alzheimer’s increased by 55 percent. According to the latest statistics, Alzheimer’s claims the lives of more than half a million Americans each year, and unless there are radical changes, many experts project half of the population will eventually develop it.
These are grim statistics, but there is hope. Mounting evidence shows both of these conditions — as well as many other top killers — are metabolic diseases. This is actually good news, because that means you can prevent, treat and recover from them like other metabolic conditions, such as Type 2 diabetes and heart disease.
Ketogenic Diet Shows Tremendous Promise as Tool Against Chronic Disease
A number of experts and researchers are now convinced the answer to our burgeoning cancer and Alzheimer’s epidemics is a ketogenic diet and other metabolic support. Nutritional ketosis is the metabolic state associated with an increased production of ketones in your liver; i.e., the biological reflection of being able to burn fat, and is defined as having blood ketones in the range of 0.5 to 3.0 millimoles per liter.
Personally, I believe metabolic therapy — starting with a ketogenic diet — is an absolutely crucial facet of dementia and cancer prevention and treatment, and hopefully some day it will be adopted as a first line of treatment by mainstream medicine. The two videos included in this article feature Dominic D’Agostino, Ph.D., assistant professor at the University of South Florida College of Medicine.
He teaches courses in molecular pharmacology and physiology, and maintains involvement in several studies researching metabolic treatments for neurological disorders such as seizures, Alzheimer’s, ALS and cancer, all of which are metabolically linked.
What Is Metabolic Therapy?
Metabolic therapy is an umbrella term that includes nutrition (primarily in the form of a ketogenic diet), dietary supplements, drugs that have a therapeutic influence on energy metabolism, fasting, hyperthermia, hyperbaric oxygen therapy and more. The focus of D’Agostino’s talk is the biological effects of nutritional ketosis and ketone supplements. The first 15 minutes or so are spent explaining the background of how he got into looking at fasting as a therapeutic aid to improve brain metabolism.
The second half of the video goes into practical applications of nutritional ketosis, and its anticancer effects. In my latest book, “Fat for Fuel,” I present a program called metabolic mitochondrial therapy (MMT), which is a form of metabolic therapy.
MMT includes not only cyclical ketosis, but also a variety of other strategies to improve your mitochondria other than diet, such as cold thermogenesis, photobiology, detox, exercise and electromagnetic field (EMF) avoidance. As noted by D’Agostino, metabolic therapies have the ability to treat a broad range of pathologies, not just cancer, making it all the more valuable from a clinical standpoint.
Ketones Fuel Your Body and Brain During Starvation
As explained by D’Agostino, it had long been thought that the brain could only function on glucose, but studies looking at the effects of starvation showed otherwise. In fact, during starvation, such as a bout of fasting, your brain switches to using ketones derived from dietary fats, as its primary fuel, and ketones actually enhance brain function. If you eat a regular diet, which tends to be higher in net carbs than fats, your brain will almost exclusively use glucose as its primary fuel.
D’Agostino cites a study in which overweight participants fasted for 40 days. After the first week, their ketones skyrocketed, overtaking glucose as the primary fuel source for the body (and brain). Studies have also shown that during fasting, at least two-thirds or more of the energy your body produces is derived from ketone bodies. “So, ketones function as an alternative fuel for the brain [when] glucose is not available,” D’Agostino explains.
Now, putting your body into starvation mode through longer water fasts is not an attractive option for most people. The good news is a ketogenic diet mimics the effects of fasting in that it elevates ketones and lowers blood glucose. The key to nutritional ketosis is twofold: You need to dramatically reduce the amount of net carbohydrates you eat (total carbs minus fiber), and you need to eat a significant amount of healthy dietary fats.
Ketogenic Diet Often Better Than Drugs for the Treatment of Epilepsy
Epilepsy is a neurological disorder marked by abnormal electrical discharges in the brain that trigger seizures. The Epilepsy Foundation suggests epilepsy is the fourth most common neurological condition, with an estimated 65 million people worldwide affected by it.1
Some 150,000 Americans are diagnosed with epilepsy annually, with children and older adults experiencing the highest incidence rates.2 Nutritional ketosis has been shown to be a very effective treatment for many epileptics, especially children who do not respond well to the medications used.
Research shows administration of synthetic ketone ester raises seizure resistance in rats by a whopping 575 percent, “which is above and beyond any anti-seizure medication that has been tried in this model,” D’Agostino notes. He then goes on to describe and explain the anticonvulsant and neuroprotective mechanism of ketones. In summary, both a ketogenic diet and synthetic ketone supplementation alters the ratio of gamma-aminobutyric acid (GABA) and glutamate in your brain.
Conditions and Diseases That Can Benefit From Ketones
Ketones — whether from nutritional ketosis or use of a ketone supplement — also enhance brain energy metabolism and increase the energy reserves in your brain. These therapeutic effects can be exploited for the benefit of many different conditions and diseases, including:
|Hypoxia (which can result from a stroke, space flight or even just exposure to high altitude)||Glucose transporter deficiency syndrome (a genetic seizure disorder)||Angelman’s syndrome (a seizure and motor dysfunction disorder)||Lou Gehrig’s disease (ALS)||Alzheimer’s disease|
|Parkinson’s disease||Epilepsy||Traumatic brain injury||Impaired wound healing||Cancer|
Some of these syndromes, glucose transporter deficiency syndrome and Angleman’s syndrome specifically, require patients to remain on a very strict ketogenic diet to avoid seizures. D’Agostino’s research suggests supplemental ketones may be used, allowing these patients to be less strict with their diet, without forgoing the benefits of strict nutritional ketosis. In terms of wound healing, ketones have been shown to increase profusion of blood into the wounded area, thereby facilitating healing.
How Ketones Affect Cancer Cells
D’Agostino has shown that oxygen, at levels that are nontoxic to healthy cells, are toxic to cancer cells. In essence, cancer cells are more vulnerable to oxygen toxicity. His team has also demonstrated that ketones are toxic to cancer cells. When cancer cells are placed in a petri dish and fed only ketones, they simply die. Healthy cells, on the other hand, will thrive in the presence of ketones without glucose.
What this and other research tells us is that healthy cells, including brain cells, have a very high degree of metabolic flexibility and are able to thrive on either glucose or ketones (obtained through your diet from carbohydrates and healthy fats respectively). Not so with cancer cells. Defects in their metabolism due to having damaged mitochondria prevent them from metabolizing ketones. For this reason, glucose is the predominant fuel that allow cancer cells to thrive.
Research by Thomas Seyfried, Ph.D., professor of biology at Boston College and a leading expert and researcher in the field of cancer metabolism and nutritional ketosis, shows that tumor growth is tightly correlated with blood glucose levels.
When glucose and glutamine levels are low, and ketone levels are high, very little tumor growth occurs, and as glucose levels rise, tumor growth increases right along with it. In fact, the fluorodeoxyglucose PET scan is a technology that shows glucose consumption in tissue, allowing you to identify and track the aggressiveness of cancer tumors.
All Cancers Arise From Mitochondrial Dysfunction
According to D’Agostino, in rats, the best results were obtained from a combination of ketogenic diet, ketone supplementation and hyperbaric oxygen therapy. In summary, the rationale for using a ketogenic diet and other metabolic therapies is to address and repair the mitochondrial defects causing the condition or disease in the first place. Again, nutritional ketosis prevents and combats cancer by:
|Optimizing mitochondrial function, mitochondrial biogenesis and energy production||Decreasing blood glucose, glycolysis and glucogenesis|
|Decreasing your insulin level||Increasing tissue oxygenation|
|Decreasing ROS generation and secondary free radicals||Downregulating oncogenes and upregulating tumor suppressor genes|
11 pounds in 22 days?
Is it REALLY possible to lose 11 lbs. of fat in 22 days? Actually yes… BUT only when you’re a level 4 fat burner. Unfortunately, most people are stuck as level 1 fat burners. So, how do you become a level 4 fat burner to lose up to 11 lbs. in 22 days? Simply eat these foods daily:
In April, 2009, researchers stunned the medical community when they reported chronic inflammation as the root cause of several major diseases.
See, every year 610,000 people in the U.S. die of heart disease. Cancer claims another 584,000...stroke 130,000...Alzheimer's disease nearly 85,000 — and the list goes on.
Truth is, we now know... chronic inflammation is responsible for 7 out of the top 10 leading causes of death in the United States! Hundreds of studies and scientific reviews prove it.
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To begin, I apologize for the dark nature of today's email.
However I promise what you'll discover today will be completely worth it.
Imagine a rotting corpse draped over your body from head to toe...
...suffocating tissue, restricting blood flow, damaging joints and infecting your healthy cells.
Shockingly, that nightmare is a reality for most:
64% of women and 74% of men carry too much body fat according to the National Institutes of Health.
It's choking their organs, assaulting their metabolism and sucking their energy dry.
But here's the worst part:
For most, this bodyfat has become "calorie-resistant":
It's completely unaffected by even the strictest diets... and most intense exercises.
This zombie fat is essentially... "dead tissue".
That's important for those who have 10, 25 or 50 or more pounds to lose...
AND for those who aren't technically overweight, but have what's called "pocket obesity"...
...unsightly patches of fat that cling to specific places, like:
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Obesity researchers have now discovered a "metabolic jumper cable":
It jolts dead bodyfat back to life.
This allows your metabolism to burn it as calories and re-energize your entire body.
First though, here's the #1 reason why bodyfat becomes calorie-resistant:
It lacks blood flow. This has 3 effects:
- Not enough oxygen or nutrients reach fat cells, so they become unresponsive..
- Released fat can't be sent to other tissues to be burned, so fat cells suck it back in...
- 3) Metabolic hormones carrying the "burn calories" message don't reach the fat cell...
All this means one thing:
Your body can't transform into energy, the 135,000+ of calories the average person stores as fat!
You become a metabolic zombie: NO energy to think. NO energy to move. NO energy to motivate.
Update: calorie-resistant bodyfat can be now removed...
The discovery of this "metabolic jumper cable" can now reverse this process:
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Not only do those layers of "zombie fat" start coming off, but your entire body just works better.
Plus, as your whole body burns more calories, those patches of pocket obesity whittle away.
This "metabolic jumper cable" isn't any exercise, machine or pill.
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It's not thyroid, leptin, ghrelin, insulin, adiponectin, HGH or any other "fat loss" hormone you may know.
And on this next page, you'll find out precisely how to unleash its calorie-burning power:
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I bet you can’t guess which muscle in your body is the #1 muscle that eliminates joint and back pain, anxiety and looking fat.
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d) Hip Flexors
Take the quiz above and see if you got the correct answer!
P.S. Make sure you check out the next page to get to know the 10 simple moves that will bring vitality back into your life!
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Is Bread Really the Staff of Life… or the Stuff of Disease?
For most us, there are few foods more comforting than bread.
Fluffy biscuits, crusty baguettes, flaky croissants… even a simple slice of toast topped with melted butter can taste like heaven.
And that smell… few scents are quite as pleasant as fresh bread baking in the oven.
But there is a lot of confusion as to where bread fits into a healthy diet.
The Bible practically commands followers to eat it: “Give us this day our daily bread…” The government put it at the base of the food pyramid. And for centuries, it has been called “the staff of life.”
Of course, there are some who disagree…
Well-known cardiologist, Dr. William Davis, calls wheat “the perfect chronic poison.”
And for a poison, we sure eat lots of it…
The average American consumes 55 pounds of wheat flour every year, making refined flour the #1 source of calories in the American Diet – a situation that nutrition expert Chris Kresser describes as, “a public health catastrophe.”
So, what is the truth about bread and wheat?
- Is it the perfect poison… or an essential daily food?
- Is “gluten-free” bread better for you than regular bread?
- And can you still eat bread… while maintaining a lean body and optimal health?
The answers to these questions may surprise you!
Be sure to read #5 – the biggest surprise of all!
Recently, Doctor of Naturopathy, weight-loss expert and best-selling Amazon author Liz Swann Miller, creator of the Red Smoothie Detox Factor, revealed 2 of the secrets to easy, steady weight loss. Secrets the big food corporations do their best to hide from us.
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Now prepare yourself for one of the biggest weight loss secrets there is. A secret that, when you use it properly, can transform your body and your health.
You probably know most of us eat too much processed food. What you may not know is that it’s full of toxic chemicals and substandard, dirt-cheap ingredients designed to make you eat more…and force you to gain weight.
Here’s how it works.
“That stuff is just a lot of calories your body can’t use,” Liz told me, “Some are poison. And all these foods are stripped of the anti-oxidants and anti-inflammatories that help your body detox. The result? Your body expends huge amounts of calories to eliminate some toxins—the rest, it stores in your fat to protect you. This is why most people are hungry all the time. They’re not getting energy they need.”
“So… what’s going on with me? Why am I losing weight but not going hungry?”
Liz paused, then dropped the bombshell.
Your body is designed to burn fat. You just have to let it.
“What? I thought we were designed to store fat?!?” We were Skyping and I was practically shouting. Then I heard Liz say…
What good is a fat reserve if you can’t burn it?
Liz continued: “You’re drinking smoothies packed with phytonutrients, anti-oxidants and anti-inflammatories that pull toxins out of you like a tractor beam. Allowing your body to burn those toxin-filled fat stores… and releasing tremendous amounts of stored energy.”
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- Which calories help you lose weight…and which ones help you gain it…
- The “diet” foods…some of them vegetables…that lead to weight gain and diabetes…
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Sponsored Health Resources
In the years that I've been working on this website project I've come across some amazing resources by some very special people. I'd like to share them with you here.
NOTE: I update these links often so please check back to see what's new!
1) Everyone knows green smoothies are healthy right? Have you heard of a “red” smoothie? If not, check out this story…
2) Forget what you've read about 10-day lemonade cleanses, 7-day detoxes with green juices and Gwyneth's gruel. All you need to do, and this is perfect for Saturday or or anytime really, is a simple 1-day cleanse.
3) This “hidden survival muscle” in your body will boost your energy levels, immune system, sexual function, strength and athletic performance when unlocked.
4) I thought it was virtually impossible for a website to be able to tell me anything even a little bit insightful after only submitting my name and date of birth... I was wrong!
5) Turmeric is amazing. The problem is - It's hard to absorb!
6) Wonder why your stomach still sticks out even though you're hammering the core exercises every day? It's a common myth that bulging belly is due to weak abdominal muscles.
7) Even if you're the most active of athletes, you may still suffer from tight hip flexors due to the amount of time you spend each day planted to a chair.
Enjoy! Let me know how these work out for you. And if you run across anything I've missed please let me know.