Intestinal flora may be the key to understanding how multiple sclerosis develops. Previous assumptions held that MS was a mostly genetic problem, prompting physicians to closely examine DNA. New research, however, has shown that autoimmune diseases such as multiple sclerosis, are brought about by a combination of environmental and genetic factors, the catalyst of which could be the balance of the gut microbiome. Should this be further verified, it could help neuroimmunologists design better treatment plans for MS patients and more importantly, craft simple and more natural preventive plans.
How does MS affect the body?
Multiple sclerosis (MS) is a disease that attacks the central nervous system. T-cells, which are a sub-type of white blood cells, begin damaging the nerve cells, destroying the sheath that surrounds these cells. As these cells die, nerve impulses can no longer transmit correctly. Patients diagnosed with the condition experience general muscle weakness, numbness, problems with memory, visual disturbances, and difficulties in balance. Those diagnosed with more severe cases of the illness are often placed in a nursing facility as they can no longer independently function. There is currently no cure for the condition.
Scientists hypothesize that every person’s T-cells have the potential to exhibit aberrant behavior, but genetic vulnerability does not dictate disease manifestation. Hertie Professor and Emeritus Director at the Max Planck Institute of Neurobiology, Professor Harmut Wekerle explains that “more than 200 genes that increase susceptibility to MS have now been identified, but for MS to develop, there must be a trigger.”
This trigger is suspected to be the natural intestinal flora.
To prove this theory, researchers from the Ludwig Maximilian University of Munich, the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the Universities of California (San Francisco) and Münster, observed 50 pairs of identical German twins, one of whom had MS while the other did not. This, the researchers said, would eliminate any genetic variability in their study. Cross-analysis of different factors showed subtle, but incredibly distinct, differences between the twins. The most intriguing was the gut microbiome profile.
“Where things got really interesting, however, is when we inoculated the genetically modified mice, which had been raised in sterile conditions, with the human microbiota,” said Guru Krishnamoorthy, a neuroimmunologist at the Max Planck Institute. The team saw that mice exposed to the intestinal flora of patients with MS developed MS-like brain lesions.
Not a cure, but may help people suffering from MS
By observing animal models, the scientists say that they eliminated any confounding factors that may be inferred in human experiments (such as individual eating habits, etc.) These results clarify the relationship between intestinal flora and T-cell activation.
The research team was quick to note that finally grasping this concept does not imply a cure for the disease. More studies need to be conducted to develop any new diagnostic procedure or treatment. All the same, this study does highlight the importance of following a healthy lifestyle, especially in keeping a balanced gut microbiome.
A brief look at multiple sclerosis
- Women are two to three times more likely to develop multiple sclerosis and have a relapse.
- Multiple sclerosis can affect anyone of any age.
- The average age for MS symptoms to first appear is between the ages of 30 to 35.
- The condition is more common among Caucasians and among those of Northern or Central European descent.
- It is estimated that there are around 200 new cases per week of MS being diagnosed in the U.S.
11 pounds in 22 days?
Is it REALLY possible to lose 11 lbs. of fat in 22 days? Actually yes… BUT only when you’re a level 4 fat burner. Unfortunately, most people are stuck as level 1 fat burners. So, how do you become a level 4 fat burner to lose up to 11 lbs. in 22 days? Simply eat these foods daily:
Did you know that one of the best times to stretch is right before bed? However…
What stretches should you do? Here’s a 1-minute stretch routine you can do before bed...
Lisa, Yoga Coach
eatlocalgrown / wisemindhealthybody
...easy, 3-minute exercise that completely cured his horrendous snoring! We can both finally sleep!
Today is a good day. Tonight will be even better. Why?
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Did you know that your bodyfat can become "calorie-resistant"?
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To your health!
PS - Studies show that it can also reduce your risk of diabetes by 53.7%, a heart attack by 83.3% and stroke by 51.4%. Here's more of the scientific proof...
I bet you can’t guess which muscle in your body is the #1 muscle that eliminates joint and back pain, anxiety and looking fat. This “hidden survival muscle” in your body will boost your energy levels, immune system, sexual function, strength and athletic performance when unlocked.
If this “hidden” most powerful primal muscle is healthy, we are healthy.
d) Hip Flexors
Take the quiz above and see if you got the correct answer!
In April, 2009, researchers stunned the medical community when they reported chronic inflammation as the root cause of several major diseases.
See, every year 610,000 people in the U.S. die of heart disease. Cancer claims another 584,000...stroke 130,000...Alzheimer's disease nearly 85,000 — and the list goes on.
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Over the past year, my friend Dave over at PaleoHacks has been working on a super secret cookbook project with our good friend Peter Servold a Le Cordon Bleu trained Chef and owner of Pete's Paleo...
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Sponsored Health Resources
In the years that I've been working on this website project I've come across some amazing resources by some very special people. I'd like to share them with you here.
NOTE: I update these links often so please check back to see what's new!
1) Everyone knows green smoothies are healthy right? Have you heard of a “red” smoothie? If not, check out this story…
2) Forget what you've read about 10-day lemonade cleanses, 7-day detoxes with green juices and Gwyneth's gruel. All you need to do, and this is perfect for Saturday or or anytime really, is a simple 1-day cleanse.
3) This “hidden survival muscle” in your body will boost your energy levels, immune system, sexual function, strength and athletic performance when unlocked.
4) I thought it was virtually impossible for a website to be able to tell me anything even a little bit insightful after only submitting my name and date of birth... I was wrong!
5) Turmeric is amazing. The problem is - It's hard to absorb!
6) Wonder why your stomach still sticks out even though you're hammering the core exercises every day? It's a common myth that bulging belly is due to weak abdominal muscles.
7) Even if you're the most active of athletes, you may still suffer from tight hip flexors due to the amount of time you spend each day planted to a chair.
Enjoy! Let me know how these work out for you. And if you run across anything I've missed please let me know.