A research team out of University of Colorado-Boulder has found that prescription opioids may actually worsen chronic pain. The study also discovered that these drugs may in fact prolong the condition that they are supposed to help placate. This may explain why in the U.S., prescriptions of opioids, such as methadone, oxycodone (such as OxyContin®) and hydrocodone (such as Vicodin®), have quadrupled since 1999.
Pain after disease/damage of the nervous system is predominantly treated with opioids, but without exploration of the long-term consequences. We demonstrate that a short course of morphine after nerve injury doubles the duration of neuropathic pain. (Source)
Prescription Painkillers are Killers
There is little contention to the claim that prescription painkillers are dangerous. They have been responsible for over 183,000 deaths over the last 15 years. Some particular brands have killed thousands. Take Vioxx, for example. This painkiller killed over 60,000 before it was pulled off the market in 2004. In the year prior, Merck made $2.5 billion from sales of Vioxx, which was heavily marketed via direct-to-consumer advertising.
“There’s an ongoing death rate from use of pain medications as prescribed. So, even as prescribed, they’re highly dangerous and they are open to abuse.” ~ Dr. Margaret Gedde, owner and founder the Clinicians’ Institute of Cannabis Medicine (Source)
Death isn’t the only risk of prescription painkillers. Misuse, abuse and addiction are rampant in the United States. For example, in 2014, almost 2 million Americans abused or were dependent on prescription opioids. Furthermore, on any given day, 1000 people on average are treated in emergency situations for the misuse of these drugs.
Why are we putting ourselves at such great risk? Based on the research out of University of Colorado-Boulder (UC-Boulder, it seems prescription painkillers aren’t actually helping people address chronic pain but are very effective in creating repeat customers for Big Pharma.
The Study: Painkillers Worsen Chronic Pain
Many people take prescription painkillers on a regular basis because the drugs are supposed to help them manage chronic pain. But a 2016 study out of CU-Boulder found that opioid use actually increases and prolongs chronic pain in rats. The study researchers concluded that “prolonged pain is an unrealized and clinically concerning consequence of the abundant use of opioids in chronic pain.” (Source)
During the study, scientists discovered that a five-day morphine treatment in rats resulted in chronic pain that continued for months. The treatment triggered the release of pain signals from the rats’ immune cells located in the spinal cord – also called glial cells. These cells play an important role in clearing out infection-causing microorganisms. When the body is experiencing pain, glial cells are placed on high alert as the body prepared for the clearing process.
During the opioid study, morphine treatment in rats resulted in opioids sending repeated signals to the glial cells. This increased the activity of these nerve cells in the spinal cord, resulting in intensified chronic pain that continued for several months.
Even brief exposure has lasting effects
“We are showing for the first time that even a brief exposure to opioids can have long-term negative effects on pain. We found the treatment was contributing to the problem.” ~ Peter Grace, CU-Boulder Assistant Research Professor and Faculty Member in the Department of Psychology and Neuroscience (Source)
“The implications for people taking opioids like morphine, oxycodone and methadone are great, since we show the short-term decision to take such opioids can have devastating consequences of making pain worse and longer lasting.” ~ Linda Watkins of CU-Boulder Professor (Source)
The study was published in the Proceedings of the National Academy of Sciences. Although it was conducted on rats, if the findings hold true to humans, this would help explain the vicious cycle of prescription painkiller abuse and the growing epidemic of opioid addiction.
11 pounds in 22 days?
Is it REALLY possible to lose 11 lbs. of fat in 22 days? Actually yes… BUT only when you’re a level 4 fat burner. Unfortunately, most people are stuck as level 1 fat burners. So, how do you become a level 4 fat burner to lose up to 11 lbs. in 22 days? Simply eat these foods daily:
Did you know that one of the best times to stretch is right before bed? However…
What stretches should you do? Here’s a 1-minute stretch routine you can do before bed...
Lisa, Yoga Coach
eatlocalgrown / wisemindhealthybody
...easy, 3-minute exercise that completely cured his horrendous snoring! We can both finally sleep!
Today is a good day. Tonight will be even better. Why?
Because you're about to learn easy throat exercises that cure (not just treated) your stubborn snoring – in 3 minutes – starting TONIGHT!
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Use them anytime, anywhere... even while stuck in traffic or watching TV.
Plus the results are permanent!
Did you know that your bodyfat can become "calorie-resistant"?
True. And it's completely unaffected by even the strictest diets... and most intense exercises.
However, there's good news- Calorie-resistant bodyfat can be now removed...
It's a little-known, calorie-burning hormone we all have... just waiting for the right spark to come alive. It's not thyroid, leptin, ghrelin, insulin, adiponectin, HGH or any other "fat loss" hormone you may know. Read more to find out precisely how to unleash its calorie-burning power:
To your health!
PS - Studies show that it can also reduce your risk of diabetes by 53.7%, a heart attack by 83.3% and stroke by 51.4%. Here's more of the scientific proof...
I bet you can’t guess which muscle in your body is the #1 muscle that eliminates joint and back pain, anxiety and looking fat. This “hidden survival muscle” in your body will boost your energy levels, immune system, sexual function, strength and athletic performance when unlocked.
If this “hidden” most powerful primal muscle is healthy, we are healthy.
d) Hip Flexors
Take the quiz above and see if you got the correct answer!
In April, 2009, researchers stunned the medical community when they reported chronic inflammation as the root cause of several major diseases.
See, every year 610,000 people in the U.S. die of heart disease. Cancer claims another 584,000...stroke 130,000...Alzheimer's disease nearly 85,000 — and the list goes on.
Truth is, we now know... chronic inflammation is responsible for 7 out of the top 10 leading causes of death in the United States! Hundreds of studies and scientific reviews prove it.
Fortunately, newer research shows you can prevent-even reverse-most major diseases by "turning off" inflammation. And in our new book, we show you how to do just that.
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Over the past year, my friend Dave over at PaleoHacks has been working on a super secret cookbook project with our good friend Peter Servold a Le Cordon Bleu trained Chef and owner of Pete's Paleo...
And today, this new incredible Paleo Cookbook is finally available to be shipped right to your door for FREE!
The cookbook is called Paleo Eats, and it's filled with over 80 chef created, insanely tasty Paleo recipes which means they are free from gluten, soy, dairy, and refined sugar.
Get your FREE copy of Paleo Eats Here. (Grab this today, because they only ordered a small batch of these cookbooks for this freebie promotion, and they will sell out FAST!)
Sponsored Health Resources
In the years that I've been working on this website project I've come across some amazing resources by some very special people. I'd like to share them with you here.
NOTE: I update these links often so please check back to see what's new!
1) Everyone knows green smoothies are healthy right? Have you heard of a “red” smoothie? If not, check out this story…
2) Forget what you've read about 10-day lemonade cleanses, 7-day detoxes with green juices and Gwyneth's gruel. All you need to do, and this is perfect for Saturday or or anytime really, is a simple 1-day cleanse.
3) This “hidden survival muscle” in your body will boost your energy levels, immune system, sexual function, strength and athletic performance when unlocked.
4) I thought it was virtually impossible for a website to be able to tell me anything even a little bit insightful after only submitting my name and date of birth... I was wrong!
5) Turmeric is amazing. The problem is - It's hard to absorb!
6) Wonder why your stomach still sticks out even though you're hammering the core exercises every day? It's a common myth that bulging belly is due to weak abdominal muscles.
7) Even if you're the most active of athletes, you may still suffer from tight hip flexors due to the amount of time you spend each day planted to a chair.
Enjoy! Let me know how these work out for you. And if you run across anything I've missed please let me know.